A ferroptosis inducer and inhibitor of the system Xc- cystine/glutamate transporter; inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 μM); induces cell death in HAP1 cells at 5 μM, an effect that can be blocked by ferrostatin-1 or deferoxamine; induces ferroptotic cell death in HT-1080 cells (EC50 = 0.15 μM); increases lipid peroxidation in HT-1080 cells at 1 μM