Immunohistochemistry: 5 μg/mL, Western Blot: 2.5 μg/mL
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Description
RNF14 Polyclonal Antibody. The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Immunogen
n/a
Other Names
Ring finger protein 14, ARA54, HFB30, TRIAD2, HRIHFB2038