Immunocytochemistry: 1:100-1:300, Immunofluorescence: 1:100-1:300, Immunoprecipitation: 1:50-1:100, Western Blot: 1:1000
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Description
RANBP9 Monoclonal Antibody (3C3). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.
Immunogen
n/a
Other Names
BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7; BPM-L; BPM90; RANBPM; RanBP7