Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (C-Term)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human, mouse
Isotype
n/a
Format
purified
Size
50 μg
Concentration
n/a
Applications
Western Blotting (WB)
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Description
Park2 functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5 and AIMP2. Park2 may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. Park2 limits the production of reactive oxygen species (ROS). Synonyms: Polyclonal Park2 antibody, Anti-Park2 antibody, Parkinson disease, autosomal recessive, juvenile 2, parkin antibody, MGC130518 antibody, PRKN antibody.
Immunogen
Park2 antibody was raised in rabbit using the C terminal of Park2 as the immunogen