產(chǎn)品名稱 SGC0946 from CAYMAN CHEMICAL COMPANY
    產(chǎn)品貨號 13967-50
    產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
    產(chǎn)品規(guī)格 50 mg
    產(chǎn)品品牌 CAYMAN CHEMICAL COMPANY
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameSGC0946
    DescriptionA potent inhibitor of DOT1L (IC50 = 0.3 nM); over 100-fold selective over other PMTs; active in cells, reducing H3K79 dimethylation in A431 and MCF10A cells (IC50s = 2.6 and 8.8 nM, respectively)
    Size50 mg
    Concentrationn/a
    Applicationsn/a
    Other Namesmethyltransferase epigenetic histone modification chromatin research inhibit inhibitor DOT1L protein PMTs enzyme methylate 3 three lysine 79 H3K79 catalyze monomethylation dimethylation trimethylation transcriptional gene DNA deoxyribonucleic acid damage repair cell cycle regulation A431 MCF10A bromine brominated analogs S-adenosylmethionine-competitive SAM-competitive EPZ004777 kills mixed lineages leukemia MLL cancers oncogenic fusion SGC 0946 Structural Genomic Consortium
    Gene, Accession, CAS #CAS: 1561178-17-3
    Catalog #13967-50
    Price
    Order / More InfoSGC0946 from CAYMAN CHEMICAL COMPANY
    Product Specific Referencesn/a
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