產(chǎn)品名稱 SGC 0946 from TOCRIS BIOSCIENCE
    產(chǎn)品貨號 4541/50
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 50 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameSGC 0946
    DescriptionHighly potent DOT1L methyltransferase inhibitor (Kd = 0.06 nM, IC50 = 0.3 nM in a radioactive assay); blocks H3K79 methylation in A431 cells and MCF10A cells. Inactive at 12 histone methyltransferases and DNMT1. Selectively kills cells transformed with the MLL-AF9 fusion oncogene in an in vitro model of leukemia; lowers levels of MLL target genes HOXA9 and Meis1. To request the negative control for SGC0946, please fill out the SGC0649 request form on the SGC website.. Purity 99%. MW (observed): 618.57
    Size50 mg
    Concentrationn/a
    Applicationsn/a
    Other Names1-[3-[[[(2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl](isopropyl)amino]propyl]-3-[4-(2,2-dimethylethyl)phenyl]urea
    Gene, Accession, CAS #n/a
    Catalog #4541/50
    Price
    Order / More InfoSGC 0946 from TOCRIS BIOSCIENCE
    Product Specific Referencesn/a
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