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Description
Rabbit IgG polyclonal antibody for Runt-related transcription factor 3(RUNX3) detection. Tested with WB in Mouse;Rat. No cross reactivity with other proteins. Runt-related transcription factor 3, also called AML2 is a protein that in humans is encoded by the RUNX3 gene. The RUNX3 gene encodes a Runt-related transcription factor, which is part of the RUNX gene family. By fluorescence in situ hybridization, RUNX3 was assigned to human chromosome 1p36.11. RUNX3 binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. It may be involved in the control of cellular proliferation and/or differentiation.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse RUNX3(186-205aa QKIEDQTKAFPDRFGDLRMR), identical to the related rat sequence.
Other Names
Runt-related transcription factor 3;Acute myeloid leukemia 2 protein;Core-binding factor subunit alpha-3;CBF-alpha-3;Oncogene AML-2;Polyomavirus enhancer-binding protein 2 alpha C subunit;PEA2-alpha C;PEBP2-alpha C;SL3-3 enhancer factor 1 alpha C subunit;SL3/AKV core-binding factor alpha C subunit;Runx3;Aml2, Cbfa3, Pebp2a3;