human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Isotype
n/a
Format
immunoaffinity purified
Size
400 μg
Concentration
2 mg/ml
Applications
WB
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Goat polyclonal antibody to RAB2. RAB2 belongs to the large RAB family of low molecular weight GTPases that are involved in intracellular membrane trafficking. It has been demonstrated that Rab2 is essential for the maturation of pre-Golgi intermediates. RAB2A and RAB2B are required for protein transport from the ER to the Golgi, RAB2A is lipid-anchored to the ER-Golgi intermediate compartment membrane while RAB2B is lipid anchored to the cytoplasmic side of the cell membrane. RAB2A has been shown to interact with GOLGA2. Detects total levels of Rab2 protein in transfected cells with GFP-Rab2a and GFP-Rab2b by Western blot.
Immunogen
Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli.
Other Names
Ras-related protein Rab-2A, Ras-related protein Rab-2B