human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Isotype
n/a
Format
immunoaffinity purified
Size
600 μg
Concentration
3 mg/ml
Applications
WB
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Description
Goat polyclonal to RAB2. RAB2 belongs to the large RAB family of low molecular weight GTPases that are involved in intracellular membrane trafficking. It has been demonstrated that Rab2 is essential for the maturation of pre-Golgi intermediates. RAB2A and RAB2B are required for protein transport from the ER to the Golgi, RAB2A is lipid-anchored to the ER-Golgi intermediate compartment membrane while RAB2B is lipid anchored to the cytoplasmic side of the cell membrane. Detects levels of Rab2b protein in transfected cells with GFP-Rab2b by Western blot. This antibody is specific for Rab2b and it barely detects Rab2a.
Immunogen
Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli.
Other Names
Ras-related protein Rab-2A, Ras-related protein Rab-2B