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Description
Mouse monoclonal to alpha Synuclein. Reacts well with alpha synuclein in Western blots and frozen and formalin fixed/paraffin embedded tissuesections. Recognizes human alpha synuclein. Synuclein alpha is the major component of Lewy bodies andLewy neuritis in sporadic PD. dementia with Lewy Bodies and Lewy Body variant of AD. Lewy bodies arecomposed of truncated and phosphorylated intermediate neurofilament proteins, alpha synuclein, ubiquitinand associated enzymes. The synuclein phosphoproteins 15 20 kDa are small highly conserved proteins invertebrates. The synuclein family includes alpha and beta synucleins and loosely related gamma synucleinand synoretin. The expression is abundant in neurons and typically localized at presynaptic terminals.
Immunogen
Purified E. coli produced human alpha-synuclein
Other Names
alpha synuclein, Alpha-synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid, Non A4 component of amyloid precursor, Non-A beta component of AD amyloid, Non-A-beta component of alzheimers disease amyloid, precursor of, Non-A4 component of amyloid precursor, Non-A4 component of amyloid, precursor of, OTTHUMP00000218549, OTTHUMP00000218551, OTTHUMP00000218552, OTTHUMP00000218553, OTTHUMP00000218554, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4, Parkinson disease familial 1, PD 1, PD1, SNCA, Snca synuclein, alpha (non A4 component of amyloid precursor), SYN, Synuclein alpha, Synuclein alpha 140, Synuclein, alpha (non A4 component of amyloid precursor), SYUA_HUMAN