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Description
Rabbit IgG polyclonal Picoband? antibody for Heat shock protein 75 kDa, mitochondrial(TRAP1) detection. Tested with WB, IHC-P in Human;Rat. No cross reactivity with other proteins. Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.
Immunogen
E.coli-derived human TRAP1 recombinant protein (Position: A571-H704). Human TRAP1 shares 91.7% and 94% amino acid (aa) sequence identity with mouse and rat TRAP1, respectively.
Other Names
Heat shock protein 75 kDa, mitochondrial;HSP 75;TNFR-associated protein 1;Tumor necrosis factor type 1 receptor-associated protein;TRAP-1;TRAP1;HSP75;