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Description
CCR5 Polyclonal Antibody. Receptors for the C-C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co-receptor. The chemokine receptor CCR 5 is one of the co-receptors used by primary isolates of HIV-1. Extracellular domains of CCR 5 are important for HIV entry into the target cells.