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Description
PE anti-human Pre-BCR. The human Pre-BCR is composed of mH chain and CD179a (VpreB)/CD179b (λ5). The mAb HSL2 reacts with a conformational epitope unique to the Pre-BCR complex. The Pre-BCR associates with the signal transducing heterodimer, CD79a/CD79b, to form the Pre-BCR complex. Pre-BCR is expressed on Pro-B and early Pre-B cells and plays a critical role in B cell development.