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Description
The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin 47, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The 47 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.
Immunogen
AKR/Cum mouse spontaneous T lymphoma cell line TK1 1