Immunohistochemistry: 1:300-1:2000, Western Blot: 1:300-1:2000
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Description
TAS2R38 Polyclonal Antibody. Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Variations in TAS2R38 are associated with the ability to taste phenylthiocarbamide (PTC tasting); also called thiourea tasting. The ability to taste the substance PTC and a number of related substances is genetically controlled. Genetic studies have demonstrated complex inheritance for this trait. For some people (and s
Immunogen
n/a
Other Names
Taste receptor type 2 member 38, T2R38, T2R61, PTC bitter taste receptor, PTC