Nitrated MW Standards, Western Blot (SOD, SOD Dimer, BSA, Myosin)
Description
Highly Purified. Western Blot nitrated MW Standards for N2700-02 and N2700-13. Nitric oxide (NO) and reactive oxygen species (ROS) are important mediators to produce harmful or protective functions. NO can react with superoxide anions (O2-), yielding the toxic oxidizing agent peroxynitrite (ONOO-). Peroxynitrite induces nitration of tyrosine residues leading to changes of protein structure and function, and alterations in signaling pathways. Antibodies to nitrotyrosine have been used to monitor the status of peroxynitrite-induced modification of proteins. Applications: Suitable for use in Western Blot using the polyclonal anti-nitrotyrosine. Not sutiable for use with monoclonal anti-nitrotyrosine.