High-Mobility Group Box 1 (HMGB1) (AA 1-215) protein
Description
High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor. Recombinant human HMGB1 was expressed in High Five insect cells and purified by conventional chromatography techniques. Alternative Names: High-mobility group box1 protein, Sulfoglucuronyl carbohydrate binding protein protein, HMGB1 protein, HMGB 1 protein, Amphoterin protein, HMGB-1, HMG1 protein, High-mobility group box1 protein, HMG3 protein, HMGB 1, HMGB-1 protein, SBP-1 protein, HMGB1, high-mobility group (nonhistone chromosomal) protein 1 protein, DKFZp686A04236, high mobility group protein 1 protein