A hydroxylquinone cannabidiol analog that exhibits potent antineoplastic activity in a variety of human cancer cell lines; inhibits the growth of human Raji and Jurkat lymphoma cells in vitro (EC50 = ~0.2 μg/ml; EC80 =1.56 μg/ml); inhibits growth of HT-29 colon cancer cells, which have been inoculated into nude mice, by more than 50% at a dose of 5 mg/kg
Size
25 mg
Concentration
n/a
Applications
Mass Spectrometry
Other Names
cannabidiols analogs antiproliferative activity endocannabinoids central CB1 peripheral CB2 non-CB receptor-mediated pharmacology receptors memory weight loss appetite neurodegeneration tumor surveillance analgesia inflammation hydroxylquinone antineoplastic human cancer cells lines inhibits inhibitors inhibition growth Raji Jurkat lymphomas in vitro HT-29 colon carcinomas neuroscience neurochemistry cannabinoids cbs sythetic analytical references standards