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Description
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparin sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder ucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. Synonyms: Polyclonal Gns antibody, Anti-Gns antibody, glucosamine, N-acetyl-6-sulfatase antibody, Gns antibody.
Immunogen
Gns antibody was raised in rabbit using the C terminal of Gns as the immunogen