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Description
Mouse Anti-LONP1 Recombinant Antibody (CBYCL-416). Provided herein is a Mouse monoclonal antibody against Human LONP1. The antibody can be used for immunoassay techniques, such as ELISA, WB. LONP1 is a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMI