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Description
Hamster Anti-TNFRSF8 Recombinant Antibody (2SH12-5F). This product is antibody recognizes TNFRSF8. The antibody 2SH12-5F immunoassay techniques such as: FuncS, FC. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [prov