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Description
Mouse Anti-RBFOX1 Recombinant Antibody (CBXF-1026). This product is a mouse antibody that recognizes RBFOX1. The antibody CBXF-1026 can be used for immunoassay techniques such as: WB, IF. The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encodin
Immunogen
Purified human recombinant protein fragment structure from E. coli. corresponding to N terminal amino acids 1-100 of Human FOX1