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Description
Rabbit Anti-Human AS160 (phospho Ser588) monoclonal antibody for ICC, IF, WB. AS160 (TBC1D4) is a GTPase-activiting protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 version of this protein promotes the insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane. This movement increases glucose uptake. Mutations associated with the gene cause Diabetes mellitus, non-insulin-dependent, 5 (NIDDM5).
Immunogen
Peptide corresponding to human Phospho-AS160 (Ser588) (aa583-aa592)