A potent, selective inhibitor of ATR (IC50 = 5 nM); inhibits the growth of LoVo colorectal adenocarcinoma cells in vitro and significantly reduces the growth of LoVo xenografts in mice
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
1233339-21-3 biochemical inhibitor inhibit cancer DNA damage repair intracellular signaling protein kinase cell cycle signal transduction ATR Rad3-related serine threonine ataxia telangiectasia AZ20 RAD-3