Immunohistochemistry: 1:200-1:500, Immunoprecipitation: 2-5 μg/mg lysate, Western Blot: 1:2,000-1:10,000
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Description
COBRA1 Polyclonal Antibody. NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).
Immunogen
n/a
Other Names
RP13-122B23.3, DKFZp586B0519, KIAA1182, NELF-B, NELFB, negative elongation factor B; negative elongation factor protein B