Immunocytochemistry: 10 μg/mL, Immunofluorescence: 10 μg/mL, Western Blot: 1-2 μg/mL
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Description
NLRC4 Polyclonal Antibody. Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NFkappa- signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family. Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner. Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (c
Immunogen
n/a
Other Names
UNQ6189/PRO20215, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF; CARD, LRR, and NACHT-containing protein; ICE-protease activating factor; NLR family CARD domain-containing protein 4; NOD-like receptor C4; caspase recruitment domain family, member 12; caspase recruitment domain-containing protein 12; ice protease-activating factor; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4