產(chǎn)品名稱(chēng) LSD1 Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號(hào) 41-3300
    產(chǎn)品價(jià)格 現(xiàn)貨詢(xún)價(jià),電話(huà):010-67529703
    產(chǎn)品規(guī)格 100 μg
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
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    Antigenic SpecificityLSD1
    Clone1B2E5
    Host SpeciesMouse
    Reactive Speciesbovine, canine, human, mouse, nonhuman primate, rat
    IsotypeIgG1, kappa
    Formatpurified
    Size100 μg
    Concentrationn/a
    ApplicationsImmunohistochemistry (Paraffin): 5-10 μg/mL, Immunoprecipitation: 5 μg, Western Blot: 1-3 μg/mL
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionLSD1 Monoclonal Antibody (1B2E5). LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein may play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the
    Immunogenn/a
    Other NamesRP1-184J9.1, AOF2, BHC110, KDM1, LSD1, BRAF35-HDAC complex protein BHC110, FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit, amine oxidase (flavin containing) domain 2, flavin-containing amine oxidase domain-containing protein 2, lysine (K)-specific demethylase 1, lysine-specific histone demethylase 1, lysine-specific histone demethylase 1A
    Gene, Accession #Entrez: 23028, 478193, 500569, 532997, 99982; Uniprot: O60341, Q6ZQ88
    Catalog #41-3300
    Price
    Order / More InfoLSD1 Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
    產(chǎn)品資料

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