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Description
p130Cas Monoclonal Antibody (CAS-14 (35B-1A4)), Biotin. The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region p130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
Immunogen
n/a
Other Names
Cas scaffolding protein family member 1, Crk-associated substrate p130Cas,breast cancer anti-estrogen resistance protein 1