peptide-ELISA: 1:32000, Western Blot: 0.01-0.1 μg/mL
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Description
AKR1C3 Polyclonal Antibody. AKR1C3 a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered w
Immunogen
n/a
Other Names
AKR1C3; DD3; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS; KIAA0119; aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II); prostaglandin F synthase; dihydrodiol dehydrogenase 3; chlordecone reductase homolog; hydroxysteroid (17-beta) dehydrogenase 5; type IIb 3-alpha hydroxysteroid dehydrogenase; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; DDX; aldo-keto reductase family 1, member C3; chlordecone reductase; dihydrodiol dehydrogenase X; type II 3a-hydroxysteroid