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| Antigenic Specificity | Ku70 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | peptide-ELISA: 1:2000, Western Blot: 0.1-0.3 μg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ku70 Polyclonal Antibody. The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and VJ recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. |
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| Immunogen | n/a |
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| Other Names | XRCC6; KU70; X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) ; CTC75; CTCBF; G22P1; ML8; TLAA ; ATP-dependent DNA helicase II, 70 kDa subunit; CTC box binding factor 75 kDa subunit; Ku autoantigen p70 subunit; OTTHUMP00000028581; thyroid autoantigen 70kD (Ku antigen); thyroid autoantigen 70kDa (Ku antigen); thyroid-lupus autoantigen p70 |
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| Gene, Accession # | Entrez: 2547; Uniprot: P12956 |
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| Catalog # | PA5-18738 |
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| Price | |
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| Order / More Info | Ku70 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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