Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
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Description
DIABLO Polyclonal Antibody. This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein.
Immunogen
n/a
Other Names
DFNA64, DIABLO-S, SMAC, SMAC3, 0610041G12Rik, diablo homolog, mitochondrial, direct IAP-binding protein with low pI, mitochondrial Smac protein, second mitochondria-derived activator of caspase