Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000
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Description
MSRB2 Polyclonal Antibody. MsrB2 (methionine sulfoxide reductase B2), also known as CBS1, MSRB, PILB, CBS-1 or CGI-131, is a 182 amino acid mitochondrial protein that is ubiquitously expressed. Belonging to the MsrB Met sulfoxide reductase family, MsrB2 acts as a catalyst for the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, MsrB2 is suggested to play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. MsrB2 utilizes zinc ions, one per subunit, as cofactors.