Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
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Description
MST1 Polyclonal Antibody. MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
Immunogen
n/a
Other Names
STE20-like kinase MST1, Mammalian STE20-like protein kinase 1, Serine/threonine protein kinase 4, Serine/threonine protein kinase Krs-2