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Description
TTR Monoclonal Antibody (2E10C5). Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculo
Immunogen
n/a
Other Names
ATTR; carpal tunnel syndrome 1;epididymis luminal protein 111; PALB; Prealbumin;|prealbumin| amyloidosis type I;TBPA; thyroxine-binding prealbumin;Transthyretin; TTR