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| Antigenic Specificity | BAK |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 μL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BAK Polyclonal Antibody. BAK belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAK localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
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| Immunogen | n/a |
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| Other Names | BCL2-antagonist/killer 1; cell death inhibitor 1; apoptosis regulator BAK; Bcl-2 homologous antagonist/killer; BCL2-like 7protein |
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| Gene, Accession # | Entrez: 578; Uniprot: Q16611 |
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| Catalog # | PA5-11377 |
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| Price | |
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| Order / More Info | BAK Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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