Recombinant Human Cyclic AMP-dependent transcription factor ATF-3 (ATF3)
Description
Purity > 85% as determined by SDS-PAGE. MW: 26.1kDa. Full Length: 1-181aa. N-terminal 6xHis-tagged. Homo sapiens (Human). This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.