Immunocytochemistry: 2 μg/mL, Immunofluorescence: 2 μg/mL, Western Blot: 0.5-2 μg/mL
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Description
PTP1B Monoclonal Antibody (3A7). Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. It is a holoenzyme shell (~450 kDa) consisting of 24 subunits of two types, H (heavy) and L (light), and capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiologic status of the cell, the ratio of H to L subunits in ferritin can vary widely. It can be viewed not only as part of a group of iron regulatory proteins that include transferrin and the transferrin receptor, but also as a member of the protein family that orchestrates the cellular defense against stress and inflammation. Ferritin is found in the liver, spleen, kidney and heart. Only a small amount is found in the