Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:100
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Description
CDH11 Monoclonal Antibody (16G5). This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Immunogen
n/a
Other Names
OB Cadherin; Cadherin 11; Osteoblast Cadherin; OSF-4