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Description
HOXB4 Polyclonal Antibody. Homeobox protein HOXB4 belongs to the Antp homeobox family which functions as sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Enforced expression of HOXB4 in human neonatal keratinocytes results in increased cellular proliferation and colony formation as well as decreased expression of the alpha-2-integrin and CD44 cell surface adhesion molecules. In fetal human skin HOXB4 protein expression was both nuclear and cytoplasmic within epidermal basal cells and in hair follicle inner and outer root sheath cells, whereas strong nuclear signals were observed in the bulge region. In adult skin,
Immunogen
n/a
Other Names
HOX-2.6, HOX2, HOX2F, homeo box 2F, homeo box B4, homeobox protein Hox-2.6, homeobox protein Hox-2F, homeobox protein Hox-B4