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Description
C21orf2 Polyclonal Antibody. Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
Immunogen
n/a
Other Names
Chromosome 21 open reading frame 2, A2, YF5, YF5/A2