Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 μg/mL
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Description
DDX46 Polyclonal Antibody. This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
Immunogen
n/a
Other Names
PRPF5, Prp5, DEAD box protein 46, PRP5 homolog, Prp5-like DEAD-box protein, RNA helicase, probable ATP-dependent RNA helicase DDX46