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Description
KIR2DL4 Monoclonal Antibody (#33), PE. Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several framework genes are found in all haplotypes. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-ba
Immunogen
n/a
Other Names
CD158D, G9P, KIR103, KIR103AS, CD158 antigen-like family member D, KIR-103AS, MHC class I NK cell receptor KIR103AS, NK cell receptor, killer Ig receptor, killer cell immunoglobulin-like receptor 2DL4, killer cell inhibitory receptor 103AS, natural killer cell inhibitory receptor