If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
KIR2DL4 Monoclonal Antibody (mAb#33), PE. CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
Immunogen
n/a
Other Names
CD158D, G9P, KIR103, KIR103AS, CD158 antigen-like family member D, KIR-103AS, MHC class I NK cell receptor KIR103AS, NK cell receptor, killer Ig receptor, killer cell immunoglobulin-like receptor 2DL4, killer cell inhibitory receptor 103AS, natural killer cell inhibitory receptor