A cephalosporin antibiotic; active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml); inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml); protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50s = <0.09-1.78, 0.44-3.63, and 2.31-5.2 mg/animal, respectively)