Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
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Description
KIR2DS4 Polyclonal Antibody. Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several framework genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand bindin
Immunogen
n/a
Other Names
CD158I, KIR1D, KIR412, KKA3, NKAT8, CD158 antigen-like family member I, KIR antigen 2DS4, MHC class I NK cell receptor, NKAT-8, P58 natural killer cell receptor clones CL-39/CL-17, killer cell immunoglobulin-like receptor 2DS4, killer inhibitory receptor 4-1-2, natural killer cell inhibitory recep