產(chǎn)品名稱 Phospho-IKK alpha/beta (Ser176, Ser180) Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號 710676
    產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
    產(chǎn)品規(guī)格 100 μg
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
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    Antigenic SpecificityPhospho-IKK alpha/beta (Ser176, Ser180)
    Clone7HCLC
    Host SpeciesRecombinant Rabbit
    Reactive Specieshuman
    IsotypeIgG
    Formatpurified
    Size100 μg
    Concentrationn/a
    ApplicationsImmunocytochemistry: 1-2 μg/mL, Immunofluorescence: 1-2 μg/mL
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionPhospho-IKK alpha/beta (Ser176, Ser180) Antibody (7HCLC), ABfinity? Rabbit Oligoclonal. IKK alpha/beta is encoded by CHUK (conserved helix-loop-helix ubiquitous kinase) and IKKB (inhibitor of kappa light polypeptide gene enhancer in B-cells) gene located in chromosome 10 and 8 respectively in humans. Upon stimulation by agents that activate the NF-kB pathway such as TNF alpha, the two subunits of IKK complex, IKK alpha and IKK -beta alongside a regulator NEMO (IKK gamma) phosphorylates IkB proteins. This targets the later for ubiquitin mediated degradation and phosphorylation of NF-kB leading to subsequent translocation to the nucleus. Phosphorylation at serine 176 and 180 located in the activation loop causes a confirmation change th
    Immunogenn/a
    Other NamesIKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16, I-kappa-B kinase 1, I-kappa-B kinase-alpha, IKK-a kinase, IkB kinase alpha subunit, TCF-16 subunit alpha, transcription factor 16, IKK-beta, IKK2, IKKB, NFKBIKB, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK-B, inhibitor of nuclear factor kappa-B kinase subunit beta, nuclear factor NF-kappa-B inhibitor kinase beta
    Gene, Accession #Entrez: 1147, 3551; Uniprot: O14920, O15111
    Catalog #710676
    Price
    Order / More InfoPhospho-IKK alpha/beta (Ser176, Ser180) Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
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