Immunohistochemistry (Paraffin): 10 μg/mL, Western Blot: 1-3 μg/mL
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Description
TAAR1 Polyclonal Antibody. TAAR1 is a 339 amino acid novel membrane protein belonging to the G protein-coupled receptor family and is activated by a broad range of monoamines and amphetamine-related psychostimulants (biogenic amines). It has two N-glycosylation sites at its N terminus and several potential protein kinase sites at its C terminus, including two serines and a single disulfide bridge. It shows lower cAMP accumulation in response to octopamine, tryptamine, dopamine and unresponsive to the classical biogenic amines norepinephrine, serotonin, and histamine. It is also known to have a chemosensory function distinct from odorant receptors and is involved in functional regulation of DAT and is a potentially important target for thera