Recombinant Human Insulin-like growth factor I (IGF1)
Description
Purity > 90% as determined by SDS-PAGE. MW: 34.7kDa. Full Length of Mature Protein: 49-118aa. N-terminal GST-tagged. Homo sapiens (Human). The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.