Recombinant Human Insulin-like growth factor I protein (IGF1) (Active)
Description
Purity > 97% as determined by SDS-PAGE and HPLC. MW: 7.7kDa. Full Length of Mature Protein: 49-118aa. tag-Free. Homo sapiens (Human). The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. {ECO:0000269|PubMed:21076856, ECO:0000269|PubMed:24132240}.