Recombinant Human Insulin-like growth factor I protein (IGF1) (Active)
Description
Purity > 90% as determined by SDS-PAGE. MW: 105.11kDa. Partial: 42-995aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Integrin a-5 belongs to the Integrin a chain family and contains 7 FG-GAP repeats. Integrin a-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin a-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.
Size
n/a
Concentration
n/a
Applications
RUO
Other Names
Integrin Alpha-5; CD49 Antigen-Like Family Member E; Fibronectin Receptor Subunit Alpha; Integrin Alpha-F; VLA-5; CD49e; ITGA5; FNRA